How stress and poor sleep affect your weight

Stress and poor sleep are two of the most overlooked contributors to weight gain — and they work against you in very similar ways.

When you are stressed, your body releases a hormone called cortisol. Chronically high cortisol levels increase cravings for sugary, salty, and fatty foods, and encourage fat storage, particularly around the waist. A 2024 review published in Clinical Obesity confirmed that long-term exposure to cortisol is increasingly linked to obesity development.*

Poor sleep makes this worse. Research shows that sleeping fewer than seven hours per night raises ghrelin (your hunger hormone) while lowering leptin, the hormone that tells you when you are full.** The result is that you feel hungrier, eat more, and reach for processed foods. It also raises cortisol levels; sustained high levels of cortisol can lead to increased insulin levels, more food cravings and poor sleep, which then becomes a cycle.***

Managing stress and prioritising sleep are not luxuries — they are essential tools for managing your weight.

References +
  1. Chao, A. M., Jastreboff, A. M., White, M. A., Grilo, C. M., & Sinha, R. (2017). Stress, cortisol, and other appetite-related hormones: Prospective prediction of 6-month changes in food cravings and weight. Obesity (Silver Spring, Md.), 25(4), 713–720. https://doi.org/10.1002/oby.21790
  2. Grover, S. et al. (2024). Glucocorticoids and HPA axis regulation in the stress–obesity connection: A comprehensive overview of biological, physiological and behavioural dimensions. Clinical Obesity. https://pmc.ncbi.nlm.nih.gov/articles/PMC11907100/
  3. Molumphy, N. & Brock, S. (2024). How Sleep Deprivation Affects Your Metabolic Health. Stanford School of Medicine. https://lifestylemedicine.stanford.edu/how-sleep-deprivation-affects-your-metabolic-health/ (Accessed: 25 August 2026)
  4. Rogers, E.M., Banks, N.F. & Jenkins, N.D.M. (2024). The effects of sleep disruption on metabolism, hunger, and satiety, and the influence of psychosocial stress and exercise: A narrative review. Diabetes & Metabolism Research and Reviews, 40, e3667. https://doi.org/10.1002/dmrr.3667

Share this article

These articles are for information purposes only. It cannot replace the diagnosis of a healthcare provider. Pharma Dynamics gives no warranty as to the accuracy of the information contained in such articles and shall not, under any circumstances, be liable for any consequences which may be suffered as a result of a user’s reliance thereon.

The information the reader is about to be referred to may not comply with the South Africa regulatory requirements. Information relevant to the South African environment is available from the Company and in the Professional Information/Patient Information Leaflet/Instructions for Use approved by the Regulatory Authority.

md logo
Welcome to My Dynamics!
  • Welcome

    Hi, I'm the My Dynamics Chat Bot. I can help you find recipes, articles, pamphlets and so much more!

    Give me a try, simply just type you question below and I will give you links to the most relevant content!